In the field of biology, particularly genetics and evolutionary studies, the term describes a postzygotic reproductive barrier. This barrier occurs when two species can hybridize, but the resulting offspring are unable to survive or develop properly. The hybrid embryo may begin development but cannot reach full term, often due to incompatible interactions between parental genes during development. A specific instance of this can occur when the gene products from the two parental species are unable to interact correctly during crucial developmental stages, leading to fatal flaws.
This form of reproductive isolation plays a crucial role in speciation. By preventing successful reproduction between diverging populations, it reinforces genetic divergence and helps maintain distinct species boundaries. Historically, understanding this phenomenon has provided invaluable insights into the genetic mechanisms underlying species formation and the evolution of reproductive isolation. It highlights the complex interplay of genes and developmental processes in determining organism viability and fitness.