These cells represent the final output neurons of the vertebrate retina. They receive signals from bipolar cells and amacrine cells, processing this information before transmitting it to the brain via the optic nerve. Their function involves integrating visual information, encoding it into action potentials, and relaying this encoded information for further processing in visual centers within the brain. In essence, they serve as a crucial link in the visual pathway, transforming complex retinal activity into a format suitable for higher-level interpretation.
Their significance stems from their role in converting light patterns into neural signals that the brain can understand. The integrity and functionality of these cells are essential for normal vision. Research into these retinal neurons provides insights into visual processing mechanisms, and their dysfunction is implicated in various visual disorders, such as glaucoma. Understanding their function has been historically important in advancing our understanding of how the visual system operates, and remains vital for developing treatments for vision-related diseases.